Análisis bibliométrico sobre el enfoque One Health y la resistencia a los antimicrobianos en sistemas agroambientales
DOI:
https://doi.org/10.18226/25253824.v10.n15.14Palabras clave:
Vigilancia genómica, uso de antibióticos, inocuidad alimentaria, genes de resistenciaResumen
La resistencia a los antimicrobianos se ha convertido en un desafío transversal en los sistemas agroalimentarios y ambientales, lo que genera demanda de evidencia comparable entre la salud humana, animal y ambiental. Este estudio examinó cuantitativamente la evolución de la investigación sobre el enfoque One Health y la resistencia a los antimicrobianos en contextos agroambientales mediante el mapeo bibliométrico de registros de Scopus recuperados el 5 de febrero de 2026. Tras la depuración temática, la limpieza de metadatos y su estandarización, el conjunto final de datos se procesó en Bibliometrix y VOSviewer mediante indicadores de productividad, redes de colaboración, ley de Lotka, ley de Bradford y RPYS. El corpus comprendió 2,515 documentos publicados entre 1981 y 2026 en 818 fuentes por 12,943 autores. El crecimiento anual alcanzó 9.87%, la coautoría media fue de 6.7 autores por documento, la colaboración internacional representó 36.22% y la tasa media de citación fue de 27.78 citas por documento. La producción científica aumentó con fuerza después de 2018 y alcanzó 612 documentos en 2025. Diecisiete revistas núcleo concentraron 833 artículos, y 117 países contribuyeron al campo, con China y Estados Unidos a la cabeza de la producción. El perfil resultante muestra un campo que integra transmisión ambiental, vigilancia genómica y gestión orientada al riesgo a lo largo de las cadenas de valor, lo que refuerza la necesidad de métricas armonizadas y de acción coordinada en bioseguridad, control de efluentes y uso prudente de antimicrobianos.
Citas
[1] Tilahun, H. E., & Efa, D. A. (2026). Antimicrobial resistance profiling of Salmonella and Escherichia coli isolates from conventional poultry farms in Hossana Town, Central Ethiopia. BMC Veterinary Research, 22(1). https://doi.org/10.1186/s12917-025-05188-8
[2] Murray, C. J., Ikuta, K. S., Sharara, F., Swetschinski, L., Robles Aguilar, G., Gray, A., Han, C., Bisignano, C., Rao, P., Wool, E., Johnson, S. C., Browne, A. J., Chipeta, M. G., Fell, F., Hackett, S., Haines-Woodhouse, G., Kashef Hamadani, B. H., Kumaran, E. A. P., McManigal, B., … Naghavi, M. (2022). Global burden of bacterial antimicrobial resistance in 2019: A systematic analysis. The Lancet, 399(10325), 629-655. https://doi.org/10.1016/S0140-6736(21)02724-0
[3] Li, C.-A., Gogoi-Tiwari, J., Wang, J., You, Z.-Y., Duan, X.-X., Li, Y., & Liu, B.-T. (2026). Genetic and virulence analysis of carbapenem-resistant Pseudomonas aeruginosa in farm animals in Shandong province, China: Implications for human health. BMC Microbiology, 26(1). https://doi.org/10.1186/s12866-025-04558-4
[4] Klein, E. Y., Van Boeckel, T. P., Martinez, E. M., Pant, S., Gandra, S., Levin, S. A., Goossens, H., & Laxminarayan, R. (2018). Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proceedings of the National Academy of Sciences of the United States of America, 115(15), E3463-E3470. https://doi.org/10.1073/pnas.1717295115
[5] Gebru, G. G., Muthupandian, S., & Kassaye, E. (2026). Prevalence and antimicrobial resistance of Escherichia coli and Klebsiella spp in dairy farm in the Tigray Region, Northern Ethiopia. BMC Microbiology, 26(1). https://doi.org/10.1186/s12866-025-04643-8
[6] Dimuccio, M. M., Conforti, V., Celentano, F. E., Circella, E., Salvaggiulo, A., Bozzo, G., & Corrente, M. (2026). Regulation of Antibiotic Use in Livestock: European and International Strategies to Prevent and Control Antimicrobial Resistance and Ensure Animal Welfare. Antibiotics, 15(1). https://doi.org/10.3390/antibiotics15010067
[7] WHO. (2025). Global antibiotic resistance surveillance report 2025. https://www.who.int/publications/i/item/9789240116337
[8] İnci, A., Özdarendeli, A., Yıldırım, A., Sohel, M. H., Özübek, S., Orkun, Ö., Yukarı, B. A., Ulu Kılıç, A., Vatansever, Z., Düzlü, Ö., Altay, K., Diop, S. D., Kızgın, A. D., Arslanhan, B. A., Şahin, S., & Aktaş, M. (2026). A Compendium Review of the Global Epidemiology of Ticks and Tick-borne Diseases: Regional Insights from Türkiye. Turkiye Parazitolojii Dergisi, 49, 1-66. https://doi.org/10.4274/tpd.galenos.2025.82713
[9] Martins, B. T. F., Rodrigues, R. da S., & Nero, L. A. (2026). Comparative pangenome analysis of Yersinia enterocolitica in a one health approach. BMC Genomics, 27(1). https://doi.org/10.1186/s12864-025-12420-0
[10] Van Boeckel, T. P., Brower, C., Gilbert, M., Grenfell, B. T., Levin, S. A., Robinson, T. P., Teillant, A., & Laxminarayan, R. (2015). Global trends in antimicrobial use in food animals. Proceedings of the National Academy of Sciences of the United States of America, 112(18), 5649-5654. https://doi.org/10.1073/pnas.1503141112
[11] Mulchandani, R., Wang, Y., Gilbert, M., & Van Boeckel, T. P. (2023). Global trends in antimicrobial use in food-producing animals: 2020 to 2030. PLOS Global Public Health, 3(2). https://doi.org/10.1371/journal.pgph.0001305
[12] Schar, D., Klein, E. Y., Laxminarayan, R., Gilbert, M., & Van Boeckel, T. P. (2020). Global trends in antimicrobial use in aquaculture. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-78849-3
[13] Wang, M., Zhao, C., Gong, W., Lin, Q., Zhang, X., Sun, F., Ma, M., Guo, T., & Wang, G. (2026). Multi-omics analysis reveals the pathobiome-host interactions in the bleaching disease of the seaweed Saccharina japonica. Microbiome, 14(1). https://doi.org/10.1186/s40168-025-02235-2
[14] Asghar, F., Hussain, Z., Habiba, T. U., & Nawaz, W. (2026). Reverse vaccinology-based identification of immunogenic membrane proteins from zoonotic multidrug-resistant Proteus vulgaris: A one health approach to cross-species vaccine development. BMC Veterinary Research, 22(1). https://doi.org/10.1186/s12917-025-05182-0
[15] Parrales, J. L., Briceño, S., Chimborazo, J., Lima, L. D., Alvarez, F. J., & Gonzalez, G. (2026). Green synthesis and antibacterial properties of Thalassiosira-microalgae decorated with silver and lignin Nanoparticles: A promising strategy for bacterial control in aquaculture. Environmental Nanotechnology, Monitoring and Management, 25. https://doi.org/10.1016/j.enmm.2026.101127
[16] Vallejo, P., Moura, A., López-Olaizola, M., Leclercq, A., Vicente, D., Lecuit, M., & Marimón, J. M. (2026). Improved detection of Listeria monocytogenes outbreaks using whole genome sequencing, Gipuzkoa, Northern Spain, 2010 to 2022. BMC Microbiology, 26(1). https://doi.org/10.1186/s12866-025-04585-1
[17] Wilkinson, J. L., Boxall, A. B. A., Kolpin, D. W., Leung, K. M. Y., Lai, R. W. S., Galban-Malag, C., Adell, A. D., Mondon, J., Metian, M., Marchant, R. A., Bouzas-Monroy, A., Cuni-Sanchez, A., Coors, A., Carriquiriborde, P., Rojo, M., Gordon, C., Cara, M., Moermond, M., Luarte, T., … Teta, C. (2022). Pharmaceutical pollution of the world’s rivers. Proceedings of the National Academy of Sciences of the United States of America, 119(8). https://doi.org/10.1073/pnas.2113947119
[18] Zhou, X., Bremer, P., & Shi, C. (2026). Plasmid-mediated antimicrobial resistance in non-typhoidal Salmonella: Serotype-specific mechanisms and ecological implications. International Journal of Food Microbiology, 450. https://doi.org/10.1016/j.ijfoodmicro.2026.111647
[19] Hendriksen, R. S., Munk, P., Njage, P., van Bunnik, B., McNally, L., Lukjancenko, O., Röder, T., Nieuwenhuijse, D., Pedersen, S. K., Kjeldgaard, J., Kaas, R. S., Clausen, P. T. L. C., Vogt, J. K., Leekitcharoenphon, P., van de Schans, M. G. M., Zuidema, T., de Roda Husman, A. M., Rasmussen, S., Petersen, B., … Aarestrup, F. M. (2019). Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. Nature Communications, 10(1). https://doi.org/10.1038/s41467-019-08853-3
[20] Feng, R., Yang, F., Li, T., Zhao, Y., Li, Q., Zhao, R., Liu, J., & Yang, Y. (2026). Environmental fate and risks of antibiotics and resistance genes in soil: Implications for One Health. Soil Ecology Letters, 8(2). https://doi.org/10.1007/s42832-026-0384-9
[21] Breyer, G. M., Torres, M. C., Rebelatto, R., Wuaden, C. R., Pastore, J., Lazzarotti, M., Nicoloso, R. da S., Dorn, M., Kich, J. D., & Siqueira, F. M. (2026). From farm to environment: The microbiome and the silent spread of antimicrobial resistance genes in soil despite manure management in swine farms. Journal of Environmental Management, 400. https://doi.org/10.1016/j.jenvman.2026.128747
[22] Ma, L., Zheng, F., Wang, L., & Zhu, D. (2026). Increasing microbial risks under co-contamination: View from virulence factor genes. Soil Ecology Letters, 8(2). https://doi.org/10.1007/s42832-026-0389-4
[23] WHO. (2015). Global action plan on antimicrobial resistance. https://www.who.int/publications/i/item/9789241509763
[24] WHO. (2022). One health joint plan of action (2022‒2026): Working together for the health of humans, animals, plants and the environment. https://www.who.int/publications/i/item/9789240059139
[25] UN Environment Programme. (2023). Bracing for Superbugs: Strengthening environmental action in the One Health response to antimicrobial resistance. https://www.unep.org/resources/superbugs/environmental-action
[26] Rakshith, B. L., Gautam, S., Asirvatham, L. G., Kshetrimayum, N., Keisham, S., Patrik, G., & Akash, A. (2025). Biofilm-associated microplastic contamination in rural soil and water: Emerging hazards to ecosystems. Science of the Total Environment, 1004. https://doi.org/10.1016/j.scitotenv.2025.180806
[27] Izah, S. C., & Ogwu, M. C. (2026). Water Scarcity and Insecurity: Causes and Consequences. En Springer Water: Part F1314 (pp. 1-24). Springer Nature. https://doi.org/10.1007/978-3-032-10602-5_1
[28] Luna-Morales, M. E., Pérez-Angón, M. Á., & Luna-Morales, E. (2023). Strengthen of a Scientific Field in Latin America: Evolutionary Computation. Journal of Scientometric Research, 12(2), 264-274. Scopus. https://doi.org/10.5530/jscires.12.2.025
[29] García, L. K. O., Alayo, W. M. H., Taboada, S. L. V., & Benites, N. I. P. (2025). BIBLIOMETRIC ANALYSIS ON BRIDGING THE DIGITAL DIVIDE AMONG UNIVERSITY STUDENTS: TRENDS AND PROSPECTS. Revista Conhecimento Online, 1, 193-220. Scopus. https://doi.org/10.25112/rco.v1.3963
[30] Aria, M., & Cuccurullo, C. (2024). bibliometrix: Comprehensive Science Mapping Analysis [Software]. https://cran.r-project.org/web/packages/bibliometrix/index.html
[31] Sulphey, M. M., AlKahtani, N. S., Senan, N. A. M., & Adow, A. H. E. (2024). A bibliometric study on organization citizenship behavior for the environment. Global Journal of Environmental Science and Management, 10(2), 891-906. Scopus. https://doi.org/10.22035/gjesm.2024.02.29
[32] Patel, S., Panchal, J., Vahora, S., Patel, A., Chauhan, H., Sharma, K., Sabara, P., Shrimali, M., Antiya, S., Malaviya, K., Trivedi, Y., & Hati, S. (2026). Whole-Genome Sequencing analysis of Extensively-Drug Resistance (XDR) and Virulence Determinants of carbapenem resistant Pseudomonas spp isolated and characterized from mastitis milk in Gujarat, India. International Dairy Journal, 175. https://doi.org/10.1016/j.idairyj.2025.106546
[33] Koskeroglu, K., Onmaz, N. E., Gundog, D. A., Gungor, C., Gungor, G., Imre, K., & Morar, A. (2026). Tracking persistent and resistant Enterococcus faecalis and E. faecium from farm to fork: Biofilm-linked risks in antibiotic resistance of isolates. Veterinary Research Communications, 50(2). https://doi.org/10.1007/s11259-025-11061-8
[34] Chueahiran, S., Heo, Y.-U., Chokmangmeepisarn, P., Nguyen, D. H. M., Morishita, M., Prukbenjakul, P., Debnath, P. P., Uchuwittayakul, A., Kim, D.-H., & Rodkhum, C. (2026). Genomic insights into Streptococcus suis serotype 6 isolated from snakeskin gourami: Host adaptation, environmental stressors, and one health implications. Aquaculture, 615. https://doi.org/10.1016/j.aquaculture.2026.743619
[35] Aminudin, M. H., Amalina, F., Ab Hamid, M. R., Sulaiman, S., Azfa, N., & Razak, A. S. A. (2026). Environmental and public health risks of antibiotic resistance gene pollution in poultry systems: Sustainability impact, transmission pathways, and mitigation strategies. Microbe (Netherlands), 10. https://doi.org/10.1016/j.microb.2026.100658
[36] Otwey, R. Y., Chapagain, S., Ghimire, U., & Dhakal, J. (2026). Salmonella in Backyard Poultry: Prevalence, Outbreaks, Trends, Antimicrobial Resistance, and Emerging Risks. Journal of Food Protection, 89(3). https://doi.org/10.1016/j.jfp.2026.100703
[37] Akter, L., Hasan, N. A., Rahman, M., Forajy, N., & Haque, M. M. (2026). Antimicrobial resistance in shrimp aquaculture: Pathways, ecosystem risks, and policy responses. Environmental Challenges, 22. https://doi.org/10.1016/j.envc.2025.101401
[38] Sun, Y., Zhang, M., Teng, Y., Yin, Y., Ran, J., Su, H., Li, H., Huang, X., Long, Z., Sun, X., Pan, H., Wang, X., & Li, M. (2026). Human activities and horizontal gene transfer shape the resistome landscapes of non-human primates. Journal of Hazardous Materials, 504. https://doi.org/10.1016/j.jhazmat.2026.141276
[39] Gobbo, A., Fraiture, M.-A., Van Poelvoorde, L., De Keersmaecker, S. C. J., Verhaegen, B., Garcia-Graells, C., Van Hoorde, K., Maloux, H., Hutse, V., Ceyssens, P.-J., & Roosens, N. (2026). Enhancing One Health Through Wastewater-Based Surveillance: Development and Validation of a Multiplex ddPCR Tool to Differentiate Human and Livestock Contributions. Water Research, 290. https://doi.org/10.1016/j.watres.2025.125024
[40] Wu, Y., Zhu, L., Li, N., Lu, C., Zhang, C., & Wang, M. (2026). Antibiotic resistance genes against “last-resort” antibiotics within the One Health framework: Dissemination, mechanisms, and AI-driven opportunities. Journal of Hazardous Materials, 504. https://doi.org/10.1016/j.jhazmat.2026.141296
[41] Wu, Y.-Y., & Lin, Y.-Y. (2026). Mitigation of antibiotic resistance genes and pathogens via black soldier fly-mediated bioconversion of chicken manure. Science of the Total Environment, 1015. https://doi.org/10.1016/j.scitotenv.2026.181409
[42] Nayakvadi, S., Prakash, K., Revanasiddappa, S. T., Gowda, R., Ramamurthy, A. S., Shome, R., & Gulati, B. R. (2026). Antimicrobial resistance and virulence profiles of MRSA and MRCoNS across the livestock–human–environment nexus in Karnataka. Microbial Pathogenesis, 211. https://doi.org/10.1016/j.micpath.2025.108259
[43] Hati, S., Vahora, S., Patel, S., Panchal, J., Patel, A., Chauhan, H., Sharma, K., Sabara, P., & Antiya, S. (2026). Whole-genome sequencing analysis of extensively-drug resistance (XDR) and virulence determinants of Acinetobacter spp. Isolated and characterized from milk and milk products in Anand, Gujarat, India. International Dairy Journal, 173. https://doi.org/10.1016/j.idairyj.2025.106486
[44] Minić-Pantić, D., Abela, B., Lehtimäki, J., Zink, A., Jensen-Jarolim, E., Fettelschoss-Gabriel, A., Traidl-Hoffmann, C., Ring, J., Schmid-Grendelmeir, P., Prélaud, P., & Taïeb, A. (2026). Examining Atopic Dermatitis Through the One Health Concept Lens. Allergy: European Journal of Allergy and Clinical Immunology, 81(2), 345-357. https://doi.org/10.1111/all.70080
[45] Ding, Y., Liu, B.-W., Wu, D., Li, H.-Z., Du, S., & Zhu, D. (2026). Effects of earthworms on soil virus-associated ARGs and resistance phenotypes in long-term field cropping systems. Journal of Hazardous Materials, 503. https://doi.org/10.1016/j.jhazmat.2026.141205
[46] Cui, H.-X., Bi, Q.-F., Ye, J., Li, Y.-C., Liao, H., & Su, J.-Q. (2026). Horizontal gene transfer between bacteriophages and their hosts is a key factor in the bloom of antibiotic resistance genes in Metaphire californica. Geoderma, 466. https://doi.org/10.1016/j.geoderma.2026.117676
[47] Dame-Korevaar, A., Kuiper, E., Gonzales, J. L., & Veldman, K. (2026). Flattening Patterns of Antimicrobial Resistance Levels in Indicator E. coli in Dutch Livestock. Zoonoses and Public Health, 73(1), 74-82. https://doi.org/10.1111/zph.70025
[48] Qureshi, K. A., Fahmy, N. A., Parvez, A., Almahasheer, H., Permatasari, D., Jaremko, M., & Abdallah, E. M. (2026). Biofilms and Antimicrobial Resistance: Mechanisms, Clinical Implications, and Emerging Interventions. Chemistry and Biodiversity, 23(2). https://doi.org/10.1002/cbdv.202501351
[49] Garcia-Vozmediano, A., Moroni, B., Marra, C., Pitti, M., Garofolo, G., Marotta, F., Di Romualdo, R., Zoppi, S., & Ru, G. (2026). From Barns to Bushes: Exploring the ECOFF-Based Non-Wild-Type Status of Campylobacter spp. in Pets, Livestock, Synanthropic Birds and Wild Animals in Northwestern Italy. Zoonoses and Public Health, 73(1), 30-44. https://doi.org/10.1111/zph.70020
[50] Albajes, R., López, M. M., & Jiménez Díaz, R. M. (2026). A claim for plant health as a key component of the one health concept. One Health, 22. https://doi.org/10.1016/j.onehlt.2025.101304
[51] Munene, A. K., Mwangi, P. M., Bebora, L. C., Mbindyo, C. M., & Maingi, J. M. (2026). Cross-domain antimicrobial resistance in poultry farming: A One Health assessment of antimicrobial use and multidrug resistance in Kiambu County, Kenya. Veterinary World, 19(1), 1-14. https://doi.org/10.14202/vetworld.2026.1-14
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2026 Walter Manuel Hoyos-Alayo
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Authors keep the copyright and cede to the journal the right of publishing first. Published works are licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, allowing the sharing of the work with recognition of the authorship and initial publication in this journal.
