Clinical characteristics of allergic reactions to seeds and analysis of prevalence and severity

Authors

  • Maria Zofia Lisiecka National Medical Institute of the Ministry of the Interior and Administration

DOI:

https://doi.org/10.18226/25253824.v8.n13.06

Keywords:

Cross-immunological reactions, Food allergy, anaphylactic shock, atopic dermatitis, treatment

Abstract

Seeds allergens are widespread factors of food allergy, for the targeted treatment of which accurate identification of the provoking product is necessary. Clinical cases of allergy to seeds, which are manifested by an allergic syndrome, are quite common. The purpose of the study was to determine the prevalence of allergic reactions to seeds, as well as to study clinical cases to better understand the causes of seed allergies and their prevention. To this end, this study selected 146 published scientific papers that were relevant to the topic of seed allergy and met all the criteria. Of these, 46 studies were studied and analysed, which were available in English and published in the public domain on various databases. The biological characteristics of these seeds, their distribution in the world, and their use in various spheres of life were studied in detail. The results of the study determined that pumpkin and fenugreek seeds cause the least number of allergic reactions, followed by poppy seeds sunflower seeds, and sesame seeds provoke the remaining reactions. The degree of damage caused by an allergic reaction can vary from the mildest in the form of hives and food reactions to severe anaphylactic reactions and even death. Thus, the collection of complaints, medical history, family and allergic history is an important part of the diagnosis, but additional methods of examination in the form of skin tests, determination of specific immunoglobulin E and experimental testing with certain seeds are crucial in the diagnosis.

References

. Nemni, A., Stern, R., Billard-Larue, C., & Guiddir, T. (2021). Seed allergy: A literature review. Revue Française d’Allergologie, 61(3), 184-192. https://doi.org/10.1016/j.reval.2020.11.003

. Gawryjołek, J., Ludwig, H., Żbikowska-Götz, M., Bartuzi, Z., & Krogulska, A. (2021). Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition, 89, 111272. https://doi.org/10.1016/j.nut.2021.111272

. Joseph, N.I., Slavin, E., Peppers, B.P., & Hostoffer, R.W. (2018). Fenugreek anaphylaxis in a pediatric patient. Therapeutic Advances in Allergy and Rhinology, 9. https://doi.org/10.1177/2152656718764134

. Bant, A., Kruszewski, J., Droszcz, W., & Stepień, K. (2005). Hypersensitivity to poppy seeds. Medical Advances, 58(7-8), 447-450. https://pubmed.ncbi.nlm.nih.gov/16425801/

. Ukleja-Sokołowska, N., Gawrońska-Ukleja, E., Żbikowska-Gotz, M., Bartuzi, Z., & Sokołowski, Ł. (2016). Sunflower seed allergy. International Journal of Immunopathology and Pharmacology, 29(3), 498-503. https://doi.org/10.1177/0394632016651648

. Ryczaj, K., Szczukocka-Zych, A., Wawszczak, M., Gawryjołek, J., Krogulska, A., Krawiec, M., Horvath, A., Szajewska, H., Santos, A., Bahnson, H.T., & Kulus, M. (2023). Development of peanut, sesame and tree nut allergy in Polish children at high risk of food allergy: A protocol for a cross-sectional study. BMJ Open, 13(11), e074168. https://doi.org/10.1136/bmjopen-2023-074168

. Khudan-Tsilo, I., Shevchuk, O., & Korda, M.M. (2018). Cytokines profile in experimental contact allergic dermatitis and use of nanoencapsulated preparations. International Journal of Medicine and Medical Research, 4(1), 71-77. https://doi.org/10.11603/ijmmr.2413-6077.2018.1.8733

. Allergen nomenclature. (2024). http://www.allergen.org

. Melnychaiko, I., & Andreychyn, S. (2023). Biological therapy of severe bronchial asthma. Bulletin of Medical and Biological Research, 5(2), 86-92. https://doi.org/10.61751/bmbr.2706-6290.2023.2.86

. Atis, S., Tutluoglu, B., Sahin, K., Yaman, M., Küçükusta, A.R., Oktay, I. (2002). Sensitization to sunflower pollen and lung functions in sunflower processing workers. Allergy, 57(1), 35-39. https://pubmed.ncbi.nlm.nih.gov/11991286/

. Ivashko, M., Burmei, S., Yusko, L., Chaikovska, T., & Boyko, N. (2023). Microbiological diagnostics: From traditional to molecular genetic methods: A literature review. Bulletin of Medical and Biological Research, 5(4), 34-41. https://doi.org/10.61751/bmbr/4.2023.34

. An, J. (2021). Anaphylaxis to sunflower seed with tolerance to sunflower oil: A case report. Medicina, 57(7), 661. https://doi.org/10.3390/medicina57070661

. Deyo, A., & O’Malley, B. (2008). Cucurbitaceae. https://academics.hamilton.edu/foodforthought/our_research_files/cucurbitaceae.pdf

. Bisognin, D.A. (2002). Origin and evolution of cultivated cucurbits. Ciência Rural, 32(5), 715-723. https://doi.org/10.1590/S0103-84782002000400028

. Schaefer, H., Renner, S.S. 2011. Phylogenetic relationships in the order cucurbitales and a new classification of the gourd family (Curbitaceae). Taxon, 60(1), 122-138. https://doi.org/10.1002/tax.601011

. Gerasymchuk, P.O., Fira, D.B., & Pavlyshyn, A.V. (2021). Assessment of quality of life related with health in the medicine. Bulletin of Medical and Biological Research, 3(1), 112-122. https://doi.org/10.11603/bmbr.2706-6290.2021.1.11882

. Yadav, M., Jain, S., Tomar, R., Prasad, G.B.K.S., & Yadav, H. (2010). Medicinal and biological potential of pumpkin: An updated review. Nutrition Research Reviews, 23(2), 184-90. https://doi.org/10.1017/S0954422410000107

. Figueredo, E., Cuesta-Herranz, J., Minguez, A., Vidarte, L., Pastor, C., de las Heras, M., Vivanco, F., & Lahoz, C. (2000). Allergy to pumpkin and cross-reactivity to other Cucurbitaceae fruits. The Journal of Allergy and Clinical Immunology, 106(2), 402-403. https://doi.org/10.1067/mai.2000.108109

. Rodríguez-Jiménez, B., Domínguez-Ortega, J., Ledesma, A., González-García, J.M., & Kindelan-Recarte, C. (2010). Food allergy to pumpkin seed. Allergologia et Immunopathologia, 38(1), 50-51. https://doi.org/10.1016/j.aller.2009.07.001

. Caubet, J.C., Hofer, M.F., Eigenmann, P.A., & Wassenberg, J. (2010). Snack seeds allergy in children. Allergy, 65(1), 136-137. https://doi.org/10.1111/j.1398-9995.2009.02155.x

. Doll, R., Johnson, J., Peppers, B.P., Tcheurekdjian, H., & Hostoffer, R. (2017). IgE-mediated anaphylactic shock caused by pumpkin seed in an adult. Annals of Allergy, Asthma & Immunology, 118(3), 377-378. https://doi.org/10.1016/j.anai.2016.12.007

. Patel, A., & Bahna, S.L. (2016). Hypersensitivities to sesame and other common edible seeds. Allergy, 71(10), 1405-1413. https://doi.org/10.1111/all.12962

. Wei, P., Zhao, F., Wang, Z., Wang, Q., Chai, X., Hou, G., & Meng, Q. (2022). Sesame (Sesamum indicum L.): A comprehensive review of nutritional value, phytochemical composition, health benefits, development of food, and industrial applications. Nutrients, 14(19), 4079. https://doi.org/10.3390/nu14194079

. Pastorello, E.A., Varin, E., Farioli, L., Pravettoni, V., Ortolani, C., Trambaioli, C., Fortunato, D., Giuffrida, M.G., Rivolta, F., Robino, A., Calamari, A.M., Lacava, L., & Conti, A. (2001). The major allergen of sesame seeds (Sesamum indicum) is a 2 S albumin. Journal of Chromatography B: Biomedical Sciences and Applications, 756(1-2), 85-93. https://doi.org/10.1016/S0378-4347(01)00073-1

. Barbarroja-Escudero, J., Sanchez-Gonzalez, M.J., Antolin-Amerigo, D., Rodriguez-Rodriguez, M., Pineda, F., & Alvarez-Mon, M. (2015). Diagnosis of IgE-mediated hypersensitivity to sesame seeds supplemented with lipid body proteins. Allergology International, 64(4), 396-398. https://doi.org/10.1016/j.alit.2015.07.001

. Gangur, V., Kelly, C., & Navuluri, L. (2005). Sesame allergy: A growing food allergy of global proportions? Annals of Allergy, Asthma & Immunology, 95(1), 4-11. https://doi.org/10.1016/S1081-1206(10)61181-7

. Asero, R., Cecchi, L., Cervone, M., Crivellaro, M., Lodi Rizzini, F., Pravettoni, V., Quercia, O., Amato, S., & Mistrello, G. (2014). Detection of 20 kDa and 32 kDa IgE-binding proteins as the major allergens in Italian sesame seed allergic patients. European Annals of Allergy and Clinical Immunology, 46(1), 22-25. https://pubmed.ncbi.nlm.nih.gov/24702869/

. Erkek, E., Şahin, S., Ince, Ü., & Özkut, K. (2012). Mucosal contact urticaria to sesame seeds. Journal of the European Academy of Dermatology and Venereology, 26(6), 790-791. https://doi.org/10.1111/j.1468-3083.2011.04134.x

. Keskinen, H., Östman, P., Vaheri, E., Tarvainen, K., Grenquist-Norden, B., Karppinen, O., Nurdman, H., & Lowensttin, H. (1991). A case of occupational asthma, rhinitis and urticaria due to sesame seed. Clinical & Experimental Allergy, 21(5), 623-624. https://doi.org/10.1111/j.1365-2222.1991.tb00856.x

. Caimmi, S., Marseglia, A., Caimmi, D., & Marseglia, G.L. (2011). Friday asthma crisis in the daughter of two bakers. International Journal of Immunopathology and Pharmacology, 24(2), 517-518. https://doi.org/10.1177/039463201102400226

. Gravett, C.M., & Motala, C. (2007). Food-dependent exercise-induced anaphylaxis associated with sesame seed ingestion – A case report. Current Allergy & Clinical Immunology, 20(4), 216-217. https://hdl.handle.net/10520/EJC21894

. Oppel, T., Thomas, P., & Wollenberg, A. (2006). Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis. International Archives of Allergy and Immunology, 140(2), 170-173. https://doi.org/10.1159/000092557

. Keskin, O., & Sekerel, B.E. (2006). Poppy seed allergy: A case report and review of the literature. Allergy and Asthma Proceedings, 27(4), 396-398. https://doi.org/10.2500/aap.2006.27.2881

. Panasoff, J. (2008). Poppy seed anaphylaxis. Journal of Investigational Allergology & Clinical Immunology, 18(3), 224-225. https://pubmed.ncbi.nlm.nih.gov/18564637/

. Løvik, M., Namork, E., Fæste, C., & Egaas, E. (2004). The Norwegian national reporting system and register of severe allergic reactions to food. The Norwegian Journal of Epidemiology, 14(2), 155-60. https://doi.org/10.5324/nje.v14i2.238

. Aurich, S., Spiric, J., Engin, A., Simon, J.C., Mahler, V., & Treudler, R. (2019). Report of a case of IgE-mediated anaphylaxis to fenugreek. Journal of Investigational Allergology & Clinical Immunology, 29(1), 56-58. https://doi.org/10.18176/jiaci.0328

. Fæste, C.K., Christians, U., Egaas, E., & Jonscher, K.R. (2010). Characterization of potential allergens in fenugreek (Trigonella foenum-graecum) using patient sera and MS-based proteomic analysis. Journal of Proteomics, 73(7), 1321-1333. https://doi.org/10.1016/j.jprot.2010.02.011

. Fæste, C.K., Namork, E., & Lindvik, H. (2009). Allergenicity and antigenicity of fenugreek proteins (Trigonella foenum-graecum) in foods. The Journal of Allergy and Clinical Immunology, 123(1), 187-194. https://doi.org/10.1016/j.jaci.2008.09.012

. Fæste, C.K., & Namork, E. (2010). Differentiated patterns of legume sensitisation in peanut-allergic patients. Food Analytical Methods, 3, 375-362. https://doi.org/10.1007/s12161-009-9096-x

. Patil, S.P., Niphadkar, P.V., & Bapat, M.M. (1997). Allergy to fenugreek (Trigonella foenum graecum). Annals of Allergy, Asthma & Immunology, 78(3), 297-300. https://doi.org/10.1016/S1081-1206(10)63185-7

. Maruyama, N., Nakagawa, T., Ito, K., Cabanos, C., Borres, M.P., Movérare, R., Tanaka, A., Sato, S., & Ebisawa, M. (2016). Measurement of specific IgE antibodies to Ses i 1 improves the diagnosis of sesame allergy. Clinical & Experimental Allergy, 46(1), 163-171. https://doi.org/10.1111/cea.12626

. Cho, C.Y., Ivens, K.O., Nowatzke, W.L., Robotham, J., Samadpour, M., Grace, T., Oliver, K.G., & Garber, E.A.E. (2020). Extension of xMAP food allergen detection assay to include sesame. Journal of Food Protection, 83(1), 129-135. https://doi.org/10.4315/0362-028X.JFP-19-304

. Galleani, C., Diéguez, M.C., Cabanillas, B., Martín-Arriscado Arroba, C., Enríquez-Matas, A., & Crespo, J.F. (2023). Sunflower (Helianthus annuus) seed allergy. Journal of Investigational Allergology & Clinical Immunology, 35(1). https://doi.org/10.18176/jiaci.0965

. Dano, D., Remington, B.C., Astier, C., Baumert, J.L., Kruizinga, A.G., Bihain, B.E., Taylor, S.L., & Kanny, G. (2015). Sesame allergy threshold dose distribution. Food and Chemical Toxicology, 83, 48-53. https://doi.org/10.1016/j.fct.2015.05.011

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Published

2024-06-26

How to Cite

Lisiecka, M. Z. (2024). Clinical characteristics of allergic reactions to seeds and analysis of prevalence and severity. Interdisciplinary Journal of Applied Science, 8(13). https://doi.org/10.18226/25253824.v8.n13.06

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Special Edition - Integrated Approaches to Global Health, Societal Recovery, and