The impact of cerebral toxoplasmosis infection in a child with HIV

Autores/as

DOI:

https://doi.org/10.18226/25253824.v10.n15.12

Palabras clave:

Cerebral toxoplasmosis, Children, HIV, Toxoplasma gondii

Resumen

Toxoplasmosis, caused by Toxoplasma gondii parasites, is one of infection diseases to be an issue health problem globally. Mostly, this disease infected to children because of the weak immune system. A cerebral toxoplasmosis is the kind of toxoplasmosis infected the brain. Besides that, the toxoplasmosis can make several acute damages such as hypertension, retinopathy disorder, and uncontrolled movements as well. However, both the delayed diagnosis and low immune response make the patient condition to be worse. Therefore, the right management treatment is needed to improve the patient condition. The treatments include a diagnosis earlier, multidisciplinary management, and treatment strategies effectively. Here, we reported a case of a girl diagnosed cerebral toxoplasmosis with HIV as her medical history. That condition made her in complicated diseases including damage on central nervous system, decrease on consciousness, hypertension, and hemodynamic instability. This study focuses on the right diagnosis accurately and promptly. The role of the multidisciplinary experts is needed such as pediatricians, infectious disease specialists, neurologists, and pediatric cardiologists. This comprehensive approach has helped to address the complex clinical challenges of the central nervous system damage and hemodynamic instability related with toxoplasmosis.

Biografía del autor/a

Muhammad Pribadi, Department of Paediatrics Infection and Tropical Disease

Doctor

Dwiyanti Puspitasari, Airlangga University

Doctor

Dominicus Husada, Airlangga University

Proffesor

Leny Kartina, Airlangga University

Doctor

Parwati Setiono, Airlangga University

Proffesor

Ismoedijanto Ismoedijanto, Airlangga University

Proffesor

Citas

[1] V. Rahmanian, K. Rahmanian, A. S. Jahromi, and S. Bokaie, “Seroprevalence of toxoplasma gondii infection : An umbrella review of updated systematic reviews and meta ‑ analyses,” 2020, doi: 10.4103/jfmpc.jfmpc.

[2] R. Wesołowski, M. Pawłowska, M. Smoguła, and K. Szewczyk-golec, “Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients,” 2023.

[3] A. Lau, M. K. Jain, J. Y. Chow, E. Kitchell, S. Lazarte, and A. Nijhawan, “Toxoplasmosis Encephalitis : A Cross-Sectional Analysis at a U . S . Safety-Net Hospital in the Late cART Era,” vol. 20, pp. 1–7, 2021, doi: 10.1177/23259582211043863.

[4] S. Dian, “Cerebral toxoplasmosis in HIV-infected patients : a review,” Pathog. Glob. Health, vol. 117, no. 1, pp. 14–23, 2023, doi: 10.1080/20477724.2022.2083977.

[5] J. Paulo, M. Telles, and J. E. Vidal, “Cerebral toxoplasmosis with neurological co-infection in people living with AIDS / HIV : results of a prospective cohort in São Paulo , Brazil Toxoplasmose cerebral com coinfecção neurológica em pessoas que vivem com HIV / AIDS : resultados de uma,” 2023.

[6] R. Zawadzki et al., “Evaluation of imaging methods in cerebral toxoplasmosis,” 2023.

[7] A. Amare, “Seizure in HIV ‑ infected patients : clinical presentation , cause and treatment outcome in Ethiopia — a retrospective study,” BMC Infect. Dis., pp. 1–7, 2021, doi: 10.1186/s12879-021-06497-7.

[8] A. K. Graham, C. Fong, A. Naqvi, and J. Lu, “Journal of the Neurological Sciences Toxoplasmosis of the central nervous system : Manifestations vary with immune responses,” J. Neurol. Sci., vol. 420, no. May 2020, p. 117223, 2021, doi: 10.1016/j.jns.2020.117223.

[9] H. M. Elsheikha and C. M. Marra, “crossm of Cerebral Toxoplasmosis,” vol. 34, no. 1, pp. 1–28, 2021.

[10] J. Layton et al., “Clinical Spectrum , Radiological Findings , and Outcomes of Severe Toxoplasmosis in Immunocompetent Hosts : A Systematic Review,” pp. 1–58, 2023.

Descargas

Publicado

2026-05-16

Cómo citar

Pribadi, M., Puspitasari, D., Husada, D., Kartina, L., Setiono, P., & Ismoedijanto, I. (2026). The impact of cerebral toxoplasmosis infection in a child with HIV. Revista Interdisciplinaria De Ciencias Aplicadas, 10(15), 1–4. https://doi.org/10.18226/25253824.v10.n15.12